abstract：:Citrate, as an anticoagulant for continuous renal replacement therapy in critically ill patients, has some potential advantages over heparin, including a prolonged dialysis filter life and reduced risk of bleeding. The key parameter involved in monitoring the adequacy and safety of citrate anticoagulation during conti...

journal_title：Anaesthesia

authors： Morgan DJ,Ho KM

更新日期：2009-12-01 00:00:00

abstract：:We aimed to determine if using the EndoFlex tracheal tube on the first intubation attempt provided improved placement times and intubation success compared with a standard-type tracheal tube in 50 patients undergoing gynaecological surgery in a prospective, randomised, cross-over trial. We found that using the EndoFle...

journal_title：Anaesthesia

authors： Teoh WH,Sia AT,Fun WL

更新日期：2009-11-01 00:00:00

abstract：:Despite being a standard procedure during induction of anaesthesia, facemask ventilation can be a major challenge especially for inexperienced anaesthetists. We manufactured a Jaw-Thrust-Device designed to keep the patient's jaws in an optimised position, and thus to maintain the airway in a permanently patent state. ...

journal_title：Anaesthesia

authors： von Goedecke A,Mitterschiffthaler L,Paal P,Mitterlechner T,Wenzel V,Herff H

更新日期：2009-11-01 00:00:00

abstract：SUMMARY:In view of the controversy over the use of inotropes in free tissue transfer surgery, we assessed the effect of different intra-operative dobutamine infusion rates on blood flow in the anastomosed recipient artery. Twenty patients undergoing head and neck tumour resection and immediate reconstructive surgery wi...

journal_title：Anaesthesia

authors： Scholz A,Pugh S,Fardy M,Shafik M,Hall JE

更新日期：2009-10-01 00:00:00

abstract：:To assess the utility of a relatively simple bedside method of estimating cardiac index during major surgery or in the intensive care unit, we conducted a prospective study in patients undergoing elective cardiac bypass surgery where a pulmonary artery catheter was inserted as part of routine monitoring. The cardiac i...

journal_title：Anaesthesia

authors： Berridge JC,Warring-Davies K,Bland JM,Quinn AC

更新日期：2009-09-01 00:00:00

abstract：:The 2001 Report of the National Confidential Enquiry into Perioperative Deaths recommended that an echocardiogram should be performed on patients with aortic stenosis prior to anaesthesia. In this study we present the patient details, management and outcome of the 272 hip fracture patients with a previously undiagnose...

journal_title：Anaesthesia

authors： McBrien ME,Heyburn G,Stevenson M,McDonald S,Johnston NJ,Elliott JR,Beringer TR

更新日期：2009-08-01 00:00:00

abstract：:We prospectively audited the bacterial contamination of re-usable analgesia infusion pumps. In a one-month period, 112 samples from the handset and keypads of our analgesia infusion pumps were cultured for bacterial contamination. Forty-five percent of handset swabs and 46% of keypad swabs grew bacteria; the commonest...

journal_title：Anaesthesia

authors： Rothwell M,Pearson D,Wright K,Barlow D

更新日期：2009-07-01 00:00:00

abstract：:The objective of the study was to determine whether dopexamine alters in-hospital mortality. The following databases were searched, Embase (1974-July 2007), Medline (1950-July 2007), CINAHL, PubMed and Cochrane Clinical Register of Controlled Trials (CENTRAL). Two reviewers independently checked the quality of the stu...

journal_title：Anaesthesia

authors： Gopal S,Jayakumar D,Nelson PN

更新日期：2009-06-01 00:00:00

abstract：:Anaesthetists have traditionally focused on technological and pharmacological advances when considering the provision of anaesthetic care. Anaesthetists are expected to be able to communicate effectively with peers, patients, their families and others in the medical community; however, few details are provided regardi...

journal_title：Anaesthesia

authors： Cyna AM,Andrew MI,Tan SG

更新日期：2009-06-01 00:00:00

abstract：:In a well-defined fast-track setup for total hip and knee arthroplasty, with a multimodal analgesic regimen consisting of intra-operative local anaesthetic infiltration and oral celecoxib, gabapentin and paracetamol for 6 days postoperatively, we conducted a prospective, consecutive, observational study. The purpose w...

journal_title：Anaesthesia

authors： Andersen LØ,Gaarn-Larsen L,Kristensen BB,Husted H,Otte KS,Kehlet H

更新日期：2009-05-01 00:00:00

abstract：:Using the Nottingham Physiology Simulator, we investigated the effects on pre-oxygenation and apnoea during rapid sequence induction of labour, obesity, sepsis, pre-eclampsia, maternal haemorrhage and multiple pregnancy in term pregnancy. Pre-oxygenation with 100% oxygen was followed by simulated rapid sequence induct...

journal_title：Anaesthesia

authors： McClelland SH,Bogod DG,Hardman JG

更新日期：2009-04-01 00:00:00

abstract：:The purpose of this study was to validate a device designed to measure activated clotting time in low-range heparin plasma concentrations (ACT-LR) prospectively during the post-operative period of vascular surgery. Measurement of ACT-LR and activated partial thromboplastin time (APTT) were performed before heparinisat...

journal_title：Anaesthesia

authors： Racioppi L,Quinart A,Biais M,Nouette-Gaulain K,Revel P,Sztark F

更新日期：2009-04-01 00:00:00

abstract：:A review is presented of animal studies of the selective steroidal neuromuscular blocking drug binding agent sugammadex. These studies demonstrate that sugammadex is faster in onset than the currently used acetylcholinesterase inhibitors, has no muscarinic effects, and is characterised by lack of adverse effects on ot...

journal_title：Anaesthesia

authors： Booij LH,van Egmond J,Driessen JJ,de Boer HD

更新日期：2009-03-01 00:00:00

abstract：:We performed a prospective, single-centre study of times to treatment of patients with life-threatening, traumatic, extra- and subdural haematomas requiring surgical evacuation between May 2006 and May 2007. The mean time to surgical decompression was 5.0 h and 32% were performed within 4 h. Patients who initially pre...

journal_title：Anaesthesia

authors： Bulters D,Belli A

更新日期：2009-03-01 00:00:00

abstract：:The present study was conducted with the aims of comparing intravenous tramadol 1, 2 and 3 mg.kg(-1) with pethidine 0.5 mg.kg(-1) for prophylaxis of postanaesthetic shivering and to find a dose of tramadol that could provide the dual advantage of antishivering and analgesic effect in the postoperative period. The stud...

journal_title：Anaesthesia

authors： Mohta M,Kumari N,Tyagi A,Sethi AK,Agarwal D,Singh M

更新日期：2009-02-01 00:00:00

abstract：:In this study, we aimed to test the hypothesis that 1-ml plain solution of 0.5% bupivacaine or 0.5% levopubivacaine administered in a subarachnoid block can provide adequate anaesthesia and operating conditions for pilonidal cyst/sinus operations performed in the prone position. There were no significant differences b...

journal_title：Anaesthesia

authors： Cuvas O,Gulec H,Karaaslan M,Basar H

更新日期：2009-01-01 00:00:00

abstract：:Arrhythmogenic right ventricular dysplasia, also called right ventricular cardiomyopathy, is a genetically determined heart muscle disease, characterised by life-threatening ventricular arrhythmias in apparently healthy young people. The primary myocardial pathology is that the myocardium of the right ventricular free...

journal_title：Anaesthesia

authors： Alexoudis AK,Spyridonidou AG,Vogiatzaki TD,Iatrou CA

更新日期：2009-01-01 00:00:00

abstract：SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...

journal_title：Anaesthesia

authors： Ngan Kee WD,Khaw KS,Lau TK,Ng FF,Chui K,Ng KL

更新日期：2008-12-01 00:00:00

abstract：:Haemophagocytic lymphohistiocytosis secondary to viral infection is an unusual but well recognised cause of bone marrow dysfunction and multiple organ failure in young patients. Two 18 year-old patients were admitted to a tertiary liver unit with features of acute liver failure, cardio-respiratory collapse and pancyto...

journal_title：Anaesthesia

authors： Berry PA,Bernal W,Pagliuca A,Sizer E,Salisbury JR,Wendon JA,Auzinger G

更新日期：2008-11-01 00:00:00

abstract：:The performance of the occlusion and Pethick tests in detecting faulty inner tubes in co-axial circle and Bain systems was compared. Twelve co-axial circle and 12 Bain anaesthetic breathing systems were tested using the occlusion and the Pethick tests. For each system, three tubes were intact, and the remaining nine h...

journal_title：Anaesthesia

authors： Szypula KA,Ip JK,Bogod D,Yentis SM

更新日期：2008-10-01 00:00:00

abstract：:The purpose of this study was to determine the optimal bolus dose of remifentanil required for the successful insertion of the laryngeal mask airway during propofol induction in children without a neuromuscular blocking agent. Twenty-six paediatric patients, aged 3-10 years, requiring anaesthesia for short ambulatory ...

journal_title：Anaesthesia

authors： Kwak HJ,Kim JY,Kim YB,Chae YJ,Kim JY

更新日期：2008-09-01 00:00:00

abstract：:We have assessed, for the first time, genotoxicity (i.e. sister chromatid exchanges and micronuclei) in anaesthetists exposed to a single volatile anaesthetic (sevoflurane) without nitrous oxide. The anaesthetists were exposed to an 8-h time-weighted average of 0.2 parts per million sevoflurane. Internists served as n...

journal_title：Anaesthesia

authors： Wiesner G,Schiewe-Langgartner F,Lindner R,Gruber M

更新日期：2008-08-01 00:00:00

abstract：:We prospectively assessed common clinical endpoints for their usefulness in avoiding hyperinflation of the cuffs of laryngeal mask airways (slight outward movement) and tracheal tubes (disappearance of an audible leak around the cuff during manual ventilation < 20 cm H(2)O) in 640 children. Cuff pressures were measure...

journal_title：Anaesthesia

authors： Ong M,Chambers NA,Hullet B,Erb TO,von Ungern-Sternberg BS

更新日期：2008-07-01 00:00:00

abstract：:National Confidential Enquiry into Patient Outcome and Death guidelines for urgent surgery recommend a fully staffed emergency operating theatre and restriction of 'after-midnight' operating to immediate life-, limb- or organ-threatening conditions. Audit performed in our institution demonstrated significant decreases...

journal_title：Anaesthesia

authors： Cosgrove JF,Gaughan M,Snowden CP,Lees T

更新日期：2008-06-01 00:00:00

abstract：:We describe the administration of anaesthesia to a patient with Angelman syndrome, which is characterised by an abnormality of chromosome 15, where a subunit of the GABA receptor is coded. This has far-reaching anaesthetic implications as many drugs used in anaesthesia are thought to act via GABA receptors. Our patien...

journal_title：Anaesthesia

authors： Ramanathan KR,Muthuswamy D,Jenkins BJ

更新日期：2008-06-01 00:00:00

abstract：:The National Patient Safety Agency (NPSA) identified practice improvements with regard to epidural injections and infusions and released a patient safety alert on 28th March 2007. Prior to this, the Obstetric Anaesthetists' Association had considered the draft document and wished to assess current compliance in UK obs...

journal_title：Anaesthesia

authors： Jones R,Swales HA,Lyons GR

更新日期：2008-05-01 00:00:00

abstract：:Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is a long and complex procedure with significant blood and fluid loss during debulking and important pathophysiological alterations during the HIPEC phase. We performed a retrospective analysis of 78 consecutive patients undergoing cytoreduct...

journal_title：Anaesthesia

authors： Schmidt C,Creutzenberg M,Piso P,Hobbhahn J,Bucher M

更新日期：2008-04-01 00:00:00

abstract：:We conducted a national postal survey of trauma anaesthetists in the UK to ascertain current practice for the peri-operative anaesthetic management in patients with fractured necks of femur. We received 155 replies from 218 questionnaires sent (71.1% response rate). Regional anaesthesia was preferred by 75.8% of respo...

journal_title：Anaesthesia

authors： Sandby-Thomas M,Sullivan G,Hall JE

更新日期：2008-03-01 00:00:00

abstract：:The purpose of this bench-top study was to determine the subatmospheric tracheal pressures that could be generated by different sizes of suction catheters when placed into the different sizes of tracheal tubes encountered in adult anaesthetic practice. Five sizes of suction catheter were studied from 8 to 16 Fr and fi...

journal_title：Anaesthesia

authors： Vanner R,Bick E

更新日期：2008-03-01 00:00:00

abstract：:Target controlled infusions of propofol use a pharmacokinetic/pharmacodynamic model to calculate an effect site concentration of the drug. We assessed the cardiovascular stability of 10 healthy patients using non-invasive thoracic bioimpedance and their 'depth' of anaesthesia using the Bispectral index after they had ...

journal_title：Anaesthesia

authors： Jack ES,Shaw M,Harten JM,Anderson K,Kinsella J

更新日期：2008-02-01 00:00:00

abstract：:The Airtraq, a novel single use indirect laryngoscope, has demonstrated promise in the normal and simulated difficult airway. We compared the ease of intubation using the Airtraq with the Macintosh laryngoscope, in patients at increased risk for difficult tracheal intubation, in a randomised, controlled clinical trial...

journal_title：Anaesthesia

authors： Maharaj CH,Costello JF,Harte BH,Laffey JG

更新日期：2008-02-01 00:00:00

abstract：:The use of intra-operative Doppler oesophageal probes provides continuous monitoring of cardiac output. This enables optimisation of intravascular volume and tissue perfusion in major abdominal surgery, which is thought to reduce postoperative complications and shorten hospital stay. Medline and EMBASE were searched u...

journal_title：Anaesthesia

authors： Abbas SM,Hill AG

更新日期：2008-01-01 00:00:00

abstract：:Each year millions of children undergo surgery in the developing world with inadequate facilities, equipment and drugs. In many hospitals, anaesthesia is largely dependent on the availability of ketamine. Application of well-established clinical techniques, particularly for postoperative pain control, would relieve un...

journal_title：Anaesthesia

authors： Hodges SC,Walker IA,Bösenberg AT

更新日期：2007-12-01 00:00:00

abstract：:Global Oximetry (GO) is an initiative launched recently in Uganda, India, the Philippines and Vietnam. The overall aims are to promote oximetry utilisation and reduce oximetry costs in lower income countries. Research objectives include studying the feasibility of cost reduction; overcoming non-cost barriers to global...

journal_title：Anaesthesia

authors： Thoms GM,McHugh GA,O'Sullivan E

更新日期：2007-12-01 00:00:00

abstract：:Both rectal diclofenac and paracetamol are commonly used to treat acute postoperative pain in children but combining them to improve the quality of analgesia is controversial. This study aimed to detect whether the pre-operative combined administration of rectal diclofenac and paracetamol is superior to either drug al...

journal_title：Anaesthesia

authors： Riad W,Moussa A

更新日期：2007-12-01 00:00:00

abstract：:We studied 45 ASA I/II children aged between 2 and 13 years scheduled for elective strabismus surgery, randomly allocated to receive either a peribulbar block or topical lidocaine 2% combined with general anaesthesia, or general anaesthesia alone. The incidence and severity of the occulocardiac reflex, the requirement...

journal_title：Anaesthesia

authors： Gupta N,Kumar R,Kumar S,Sehgal R,Sharma KR

更新日期：2007-11-01 00:00:00

abstract：:We investigated modifications to the reservoir tube usually used in drawover anaesthetic breathing systems as a method of improving its efficiency and performance. The resulting oxygen concentration was recorded at different oxygen flow rates whilst an artificial lung was being ventilated over a range of minute volume...

journal_title：Anaesthesia

authors： Eales M,Rowe P,Tully R

更新日期：2007-11-01 00:00:00

abstract：:A prospective, randomised, double-blind study was conducted to compare the efficacy of two doses of levobupivacaine combined with sufentanil for continuous epidural infusion following thoractomy. A total of 72 patients undergoing lobectomy or pneumonectomy were enrolled. An epidural catheter was inserted between the l...

journal_title：Anaesthesia

authors： De Cosmo G,Congedo E,Mascia A,Adducci E,Lai C,Aceto P

更新日期：2007-10-01 00:00:00

abstract：:This study evaluated the ability of prehospital providers who had no previous training in intubation, to use an Airtraq laryngoscope to intubate a manikin model of a Cormack and Lehane grade III/IV view. Volunteers attending the Australian College of Ambulance Professionals conference, Adelaide, in November 2006 recei...

journal_title：Anaesthesia

authors： Woollard M,Mannion W,Lighton D,Johns I,O'meara P,Cotton C,Smyth M

更新日期：2007-10-01 00:00:00

abstract：:This randomised, placebo-controlled study assessed the effects of midazolam premedication on children's postoperative cognition and physical morbidity. In all, 179 children aged 5-10 years were randomly assigned to receive buccal midazolam (0.2 mg x kg(-1)) or placebo before sevoflurane-nitrous oxide anaesthesia for m...

journal_title：Anaesthesia

authors： Millar K,Asbury AJ,Bowman AW,Hosey MT,Martin K,Musiello T,Welbury RR

更新日期：2007-09-01 00:00:00